NCBI Accession #
NP_196497.1
NCBI GenBank Nucleotide #
NM_120971.3
NCBI Official Full Name
phosphatidylinositol 4-OH kinase beta2
NCBI Official Symbol
PI-4KBETA2
NCBI Official Synonym Symbols
phosphatidylinositol 4-OH kinase beta2; PHOSPHATIDYLINOSITOL 4-OH KINASE BETA2; PI4KBETA2; T5E8.150; T5E8_150
NCBI Protein Information
phosphatidylinositol 4-OH kinase beta2
NCBI Summary
Encodes a phosphatidylinositol 4-OH kinase, PI-4Kbeta2. Arabidopsis contains 12 PI-4Ks in three separate families: PI-4Kalphs, PI-4kbeta, and PI-4Kgamma. PI-4Kbeta2 is 83% identical to PI-4kbeta1 encoded by At5g64070. Important for polarized root hair growth as the loss of this gene and its close relative PI-4kbeta1, leads to the formation of abnormal root hairs.
UniProt Synonym Gene Names
PI4KBETA2; PI4-kinase beta 2; PtdIns-4-kinase beta 2; AtPI4Kbeta2; PI-4Kbeta2
UniProt Protein Name
Phosphatidylinositol 4-kinase beta 2
UniProt Synonym Protein Names
Phosphatidylinositol 4-OH kinase beta2; AtPI4Kbeta2; PI-4Kbeta2
UniProt Primary Accession #
Q0WPX9
UniProt Secondary Accession #
Q9FY80
UniProt Related Accession #
Q0WPX9
UniProt Comments
Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5-trisphosphate . Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB1, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB1 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway.