NCBI Accession #
NP_194243.1
NCBI GenBank Nucleotide #
NM_118645.4
NCBI Official Full Name
peptide met sulfoxide reductase 4
NCBI Official Symbol
PMSR4
NCBI Official Synonym Symbols
F24A6.2; methionine sulfoxide reductase A4; MSRA4; peptide met sulfoxide reductase 4
NCBI Protein Information
peptide met sulfoxide reductase 4
NCBI Summary
Encodes a chloroplast-localized methionine sulfoxide reductase that is a member of the MSRA family. Involved in protection of chloroplasts from oxidative stress.
UniProt Synonym Gene Names
PMSR; PMSR4; AtMSRA4; Peptide Met(O) reductase
UniProt Protein Name
Peptide methionine sulfoxide reductase A4, chloroplastic
UniProt Synonym Protein Names
Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase; Protein-methionine-S-oxide reductase
UniProt Primary Accession #
P54150
UniProt Secondary Accession #
Q8LAX4; Q94A72; Q9SW13
UniProt Related Accession #
P54150
UniProt Comments
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. Prevents the methionine sulfoxidation of the heat shock protein HSP21 and its subsequent inactivation. MSRA family specifically reduces the MetSO S-enantiomer.