NCBI Accession #
NP_194824.1
NCBI GenBank Nucleotide #
NM_119243.3
NCBI Official Full Name
omega-6 fatty acid desaturase
NCBI Official Symbol
FAD6
NCBI Official Synonym Symbols
CHLOROPLAST PRECURSOR; F6I18.140; F6I18_140; FAD6; FADC; fatty acid desaturase 6; FATTY ACID DESATURASE C; OMEGA-6 FATTY ACID DESATURASE; SFD4; STEAROYL DESATURASE DEFICIENCY 4
NCBI Protein Information
omega-6 fatty acid desaturase
NCBI Summary
Chloroplastic enzyme responsible for the synthesis of 16:2 and 18:2 fatty acids from galactolipids, sulpholipids and phosphatidylglycerol. Uses ferredoxin as electron donor. Gene mutation resulted in reduced level of unsaturated fatty acids leading to susceptibility to photoinhibition.
UniProt Synonym Gene Names
FADC
UniProt Protein Name
Omega-6 fatty acid desaturase, chloroplastic
UniProt Entry Name
FAD6C_ARATH
UniProt Primary Accession #
P46312
UniProt Secondary Accession #
Q9M094
UniProt Related Accession #
D85362
UniProt Comments
Function: Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol.Pathway: Lipid metabolism; polyunsaturated fatty acid biosynthesis.Subcellular location: Plastid › chloroplast inner membrane; Multi-pass membrane protein. Developmental stage: Highest levels found in expanding leaves.Domain: The histidine box domains may contain the active site and/or be involved in metal ion binding.Sequence similarities: Belongs to the fatty acid desaturase family.