NCBI Accession #
Q10LJ0.1
NCBI Official Full Name
Nuclear cap-binding protein subunit 1
NCBI Official Symbol
LOC4332822
NCBI Official Synonym Symbols
ABH1; CBP80; OsJ_10823
NCBI Protein Information
LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 1-like
UniProt Synonym Gene Names
CBP80; CBP80; NCBP 80 kDa subunit
UniProt Protein Name
Nuclear cap-binding protein subunit 1
UniProt Synonym Protein Names
80 kDa nuclear cap-binding protein; CBP80; NCBP 80 kDa subunit
UniProt Primary Accession #
Q10LJ0
UniProt Secondary Accession #
Q9AWB3; A0A0N7KH92; B9F8F3
UniProt Related Accession #
Q10LJ0
UniProt Comments
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap structure .