Narcissus pseudonarcissus Lectin (NPL/NPA) - Pure
Description
Narcissus lectin (NPL/NPA) is an affinity purified substance consisting of four subunits. It can agglutinate rabbit red blood cells, but has no response to human red blood cells. NPA has an isoelectric point between pH 4.2 and pH 4.6 and has specific binding activity for D-mannose, although studies have shown that purified lectins may have a greater affinity for internal mannose residues than for non-reducing terminal units. Buffer wash column eluted sugar - methyl mannoside. Human studies have found that NPA is almost non-mitotic, but mitosis of NPA has been reported to be age-related through an in vitro study, and the lymphocyte proliferative response of peripheral mononuclear cells (PBMC) in umbilical cord blood increases by 7 times compared to adult blood. NPA has also been found to be mitotic to PBMC in lambs but not in adult sheep.
Product Info
For research use only, not for clinical use.