NCBI Accession #
NP_001275317.1
NCBI GenBank Nucleotide #
NM_001288388.1
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Symbol
LOC102594243
NCBI Official Synonym Symbols
CI-76kD
NCBI Protein Information
NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial
UniProt Gene Name
CI-76kD
UniProt Synonym Gene Names
CI-76kD
UniProt Protein Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 1, mitochondrial
UniProt Synonym Protein Names
76 kDa mitochondrial complex I subunit; Complex I-76kD; CI-76kD; NADH-ubiquinone oxidoreductase 76 kDa subunit
UniProt Primary Accession #
Q43644
UniProt Related Accession #
Q43644
UniProt Comments
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone . This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized .