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MLO-like protein 8 (MLO8), Recombinant Protein
Cat: RP00042
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana MLO-like protein 8 (MLO8)
Product Synonym Names
Recombinant MLO-like protein 8 (MLO8); MLO-like protein 8; AtMlo8
Product Gene Name
MLO8 recombinant protein
Product Synonym Gene Name
MLO8
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MGIIDGSLLR RLICLCLWCL LGGGVTVVTA EDEKKVVHKQ LNQTPTWAVA AVCTFFIVVS VLLEKLLHKV GKVLWDRHKT ALLDALEKIK AELMVLGFIS LLLTFGQTYI LDICIPSHVA RTMLPCPAPN LKKEDDDNGE SHRRLLSFEH RFLSGGEASP TKCTKEGYVE LISAEALHQL HILIFFLAIF HVLYSFLTMM LGRLKIRGWK HWENETSSHN YEFSTDTSRF RLTHETSFVR AHTSFWTRIP FFFYVGCFFR QFFRSVGRTD YLTLRNGFIA VHLAPGSQFN FQKYIKRSLE DDFKVVVGVS PVLWGSFVLF LLLNIDGFKM MFIGTAIPVI IILAVGTKLQ AIMTRMALGI TDRHAVVQGM PLVQGNDEYF WFGRPHLILH LMHFALFQNA FQITYFFWIW YSFGSDSCYH PNFKIALVKV AIALGVLCLC SYITLPLYAL VTQMGSRMKK SVFDEQTSKA LKKWRMAVKK KKGVKATTKR LGGDGSASPT ASTVRSTSSV RSLQRYKTTP HSMRYEGLDP ETSDLDTDNE ALTPPKSPPS FELVVKVEPN KTNTGETSRD TETDSKEFSF VKPAPSNESS QDR
Sequence Positions
1-593
Chromosome Location
Chromosome: 2; NC_003071.7 (7590295..7594090, complement). Location: chromosome: 2
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
67,212 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
MLO-like protein
NCBI/Uniprot Data
NCBI Accession #
NP_565416.1
NCBI GI #
18398444
NCBI GenBank Nucleotide #
NM_127302.2
NCBI GeneID
816254
NCBI Official Full Name
MLO-like protein 8
NCBI Official Symbol
MLO8
NCBI Official Synonym Symbols
ATMLO8; F5J6.21; MILDEW RESISTANCE LOCUS O 8; MLO8
NCBI Protein Information
MLO-like protein 8
NCBI Summary
A member of a large family of seven-transmembrane domain proteins specific to plants, homologs of the barley mildew resistance locus o (MLO) protein. The Arabidopsis genome contains 15 genes encoding MLO proteins, with localization in plasma membrane. Phylogenetic analysis revealed four clades of closely-related AtMLO genes. ATMLO8 belongs to the clade III, with AtMLO5, AtMLO7, AtMLO9, and AtMLO10. The gene is expressed during seedling growth, in cotyledons and hypocotyl, and in fruit abscission zone, as shown by GUS activity patterns. The expression of several phylogenetically closely-related AtMLO genes showed similar or overlapping tissue specificity and analogous responsiveness to external stimuli, suggesting functional redundancy, co-function, or antagonistic function(s).
UniProt Gene Name
MLO8
UniProt Synonym Gene Names
AtMlo8
UniProt Protein Name
MLO-like protein 8
UniProt Entry Name
MLO8_ARATH
UniProt Primary Accession #
O22757
UniProt Secondary Accession #
Q94KB5; Q9SHM0
UniProt Related Accession #
O22757
UniProt Comments
Function: May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins By similarity.Subcellular location: Membrane; Multi-pass membrane protein By similarity. Domain: The C-terminus contains a calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion By similarity.Sequence similarities: Belongs to the MLO family.
For research use only, not for clinical use.