Mitotic spindle checkpoint protein MAD2 (MAD2), Recombinant Protein
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Mitotic spindle checkpoint protein MAD2 (MAD2), Recombinant Protein

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Cat: RP01898
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Mitotic spindle checkpoint protein MAD2 (MAD2)
Product Gene Name
MAD2 recombinant protein
Product Synonym Gene Name
MAD2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MASKTAAAKD IITLHGSAAI VSEFFCYAAN SILYNRAVYP EESFVKVKKY GLPMLLIEDE SVKSFMSNLT SQISEWLEAG KLQRVVLVIM SKATGEVLER WNFRIETDNE VVDKGVSREK SDKEIMREIQ AIMRQVASSV TYLPCLDETC VFDVLAYTDT DVAVPFTWIE SDPKLIANPQ MVKLHGFDTK IHKVDTLVSY KNDEWDEEE
Sequence Positions
1-209, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
23,731 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Mitotic spindle checkpoint protein

NCBI/Uniprot Data

NCBI Accession #
NP_189227.1
NCBI GI #
15230956
NCBI GenBank Nucleotide #
NM_113502.3
NCBI GeneID
822195
NCBI Official Full Name
DNA-binding HORMA family protein
NCBI Official Symbol
MAD2
NCBI Official Synonym Symbols
AtMAD2; MITOTIC ARREST-DEFICIENT 2
NCBI Protein Information
DNA-binding HORMA family protein
NCBI Summary
Encodes MAD2 (MITOTIC ARREST-DEFICIENT 2). May have the spindle assembly checkpoint protein functions conserved from yeast to humans.
UniProt Gene Name
MAD2
UniProt Protein Name
Mitotic spindle checkpoint protein MAD2
UniProt Synonym Protein Names
Mitotic arrest deficient protein 2
UniProt Primary Accession #
Q9LU93
UniProt Secondary Accession #
Q67YV5
UniProt Related Accession #
Q9LU93
UniProt Comments
Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and delays the onset of anaphase when this process is not complete. It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

For research use only, not for clinical use.