NCBI Accession #
NP_001031751.1
NCBI GenBank Nucleotide #
NM_001036674.2
NCBI Official Full Name
MAP kinase kinase 2
NCBI Official Symbol
MKK2
NCBI Official Synonym Symbols
ATMKK2; F27B13.50; F27B13_50; MAP KINASE KINASE 1; MAP kinase kinase 2; MK1
NCBI Protein Information
MAP kinase kinase 2
NCBI Summary
encodes a MAP kinase kinase 2 that regulates MPK6 and MPK4 in response to cold and salt stresses. Co-expression with MEKK1 in protoplasts activated MKK2 activity, suggesting that MEKK1 may be a regulator of MKK2.
UniProt Synonym Gene Names
MAP2K; MK1; AtMAP2Kbeta; AtMKK2; MAP kinase kinase 2
UniProt Protein Name
Mitogen-activated protein kinase kinase 2
UniProt Primary Accession #
Q9S7U9
UniProt Secondary Accession #
O80395
UniProt Related Accession #
Q9S7U9
UniProt Comments
MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Plays a role in abiotic stress tolerance and plant disease resistance through activation of MPK4 and MPK6 by phosphorylation. Acts redundantly with MKK1.