Metacaspase-8 (AMC8), Recombinant Protein
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Metacaspase-8 (AMC8), Recombinant Protein

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Cat: RP01706
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Metacaspase-8 (AMC8)
Product Gene Name
AMC8 recombinant protein
Product Synonym Gene Name
AMC8
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAKKALLIGI NYPGTAVELR GCVNDVHRMQ KCLIELYGFA NKDIVIMIDT DKSCIQPTGK NICDELDNLI ASGQSGDFLV FHYSGHGTRI PPGIEDSEDP TGFDECITPC DMNLIKDQQF REMVSRVKEG CQLTIISDSC HSGGLIQEVK EQIGESHMKP VDKVKEQIEE SHMKQPKLGI ASYFLNIVMN LLATCGVSKS QRDRGGGEES FRGEIELEKD ETLDIKTRYL PFESYLSLLK EQTGQTNIEP VRIRQTLLKL FGEDPSPNRQ RGLSDLGNCE VDAGDSGASR LNAVTDNGIL LSGCQTDQRS EDVYVTRTGK AYGAFSDAIQ MILSAPRKDK KKITNKELVS EARVFLKKRG YSQRPGLYCH DRFVDKPFIC Y
Sequence Positions
1-381, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
42,521 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Metacaspase

NCBI/Uniprot Data

NCBI Accession #
NP_173092.1
NCBI GI #
15219249
NCBI GenBank Nucleotide #
NM_101508.4
NCBI GeneID
838212
NCBI Official Full Name
metacaspase 8
NCBI Official Symbol
MC8
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA METACASPASE 8; ATMC8; AtMCP2e; F3O9.22; F3O9_22; MCP2e; metacaspase 2e; metacaspase 8
NCBI Protein Information
metacaspase 8
NCBI Summary
Encodes a metacaspase (cysteine-type endopeptidase) that is involved in promoting programmed cell death in response to hydrogen peroxide (H2O2), UV light, and methyl viologen (MV). Transcript levels rise in response to UV-C, H2O2, and MV. In vitro assays demonstrate that this enzyme has a preference for cleaving after an arginine residue, and it has a pH optimum of 8.0.
UniProt Gene Name
AMC8
UniProt Synonym Gene Names
MCP2E; AtMC8; AtMCP2e
UniProt Protein Name
Metacaspase-8
UniProt Synonym Protein Names
Metacaspase 2e; AtMCP2e
UniProt Primary Accession #
Q9SA41
UniProt Secondary Accession #
Q683B3
UniProt Related Accession #
Q9SA41
UniProt Comments
Cysteine protease that cleaves specifically after arginine residues. Does not cleave caspase-specific substrates. May be involved in the modulation of programmed cell death activated by oxidative stress.

For research use only, not for clinical use.