NCBI Accession #
NP_001189713.1
NCBI GenBank Nucleotide #
NM_001202784.1
NCBI Official Full Name
Glucose-1-phosphate adenylyltransferase family protein
NCBI Official Symbol
CYT1
NCBI Official Synonym Symbols
CYTOKINESIS DEFECTIVE 1; EMB101; EMBRYO DEFECTIVE 101; GDP-MANNOSE PYROPHOSPHORYLASE 1; GMP1; SENSITIVE TO OZONE 1; SOZ1; T5I7.7; T5I7_7; VITAMIN C DEFECTIVE 1; VTC1
NCBI Protein Information
Glucose-1-phosphate adenylyltransferase family protein
NCBI Summary
Encodes a GDP-mannose pyrophosphorylase/ mannose-1-pyrophosphatase. This enzyme provides GDP-mannose, which is used for cell wall carbohydrate biosynthesis and protein glycosylation as well as for ascorbate (vitamin C) biosynthesis. Mutations in this gene confer hypersensitivity to NH4+.
UniProt Synonym Gene Names
EMB101; GMP1; HSN1; SOZ1; VTC1
UniProt Protein Name
Mannose-1-phosphate guanylyltransferase 1
UniProt Synonym Protein Names
GDP-mannose pyrophosphorylase 1; Protein CYTOKINESIS DEFECTIVE 1; Protein EMBRYO DEFECTIVE 101; Protein HYPERSENSITIVE TO AMMONIUM ION 1; Protein SENSITIVE TO OZONE 1; Protein VITAMIN C DEFECTIVE 1
UniProt Primary Accession #
O22287
UniProt Secondary Accession #
Q9C5B8
UniProt Related Accession #
O22287
UniProt Comments
Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate.