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MADS-box protein FLOWERING LOCUS C (FLC), Recombinant Protein
Cat: RP00279
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana MADS-box protein FLOWERING LOCUS C (FLC)
Product Gene Name
FLC recombinant protein
Product Synonym Gene Name
FLC
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MGRKKLEIKR IENKSSRQVT FSKRRNGLIE KARQLSVLCD ASVALLVVSA SGKLYSFSSG DNLVKILDRY GKQHADDLKA LDHQSKALNY GSHYELLELV DSKLVGSNVK NVSIDALVQL EEHLETALSV TRAKKTELML KLVENLKEKE KMLKEENQVL ASQMENNHHV GAEAEMEMSP AGQISDNLPV TLPLLN
Sequence Positions
1-196, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
21,865 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
MADS-box protein
NCBI/Uniprot Data
NCBI Accession #
NP_196576.1
NCBI GI #
15238067
NCBI GenBank Nucleotide #
NM_121052.3
NCBI GeneID
830878
NCBI Official Full Name
K-box region and MADS-box transcription factor family protein
NCBI Official Symbol
FLC
NCBI Official Synonym Symbols
AGAMOUS-like 25; AGL25; FLF; FLOWERING LOCUS C; FLOWERING LOCUS F; MADS BOX PROTEIN FLOWERING LOCUS F; REDUCED STEM BRANCHING 6; RSB6; T31P16.130; T31P16_130
NCBI Protein Information
K-box region and MADS-box transcription factor family protein
NCBI Summary
MADS-box protein encoded by FLOWERING LOCUS C - transcription factor that functions as a repressor of floral transition and contributes to temperature compensation of the circadian clock. Expression is downregulated during cold treatment. Vernalization, FRI and the autonomous pathway all influence the state of FLC chromatin. Both maternal and paternal alleles are reset by vernalization, but their earliest activation differs in timing and location. Histone H3 trimethylation at lysine 4 and histone acetylation are associated with active FLC expression, whereas histone deacetylation and histone H3 dimethylation at lysines 9 and 27 are involved in FLC repression. Expression is also repressed by two small RNAs (30- and 24-nt) complementary to the FLC sense strand 3? to the polyA site. The small RNAs are most likely derived from an antisense transcript of FLC. Interacts with SOC1 and FT chromatin in vivo. Member of a protein complex.
UniProt Gene Name
FLC
UniProt Synonym Gene Names
FLF
UniProt Protein Name
MADS-box protein FLOWERING LOCUS C
UniProt Synonym Protein Names
MADS-box protein FLOWERING LOCUS F
UniProt Primary Accession #
Q9S7Q7
UniProt Related Accession #
Q9S7Q7
UniProt Comments
Putative transcription factor that seems to play a central role in the regulation of flowering time in the late-flowering phenotype by interacting with 'FRIGIDA', the autonomous and the vernalization flowering pathways. Inhibits flowering by repressing 'SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1'.
For research use only, not for clinical use.