LRR receptor-like serine/threonine-protein kinase FLS2 (FLS2), Recombinant Protein
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LRR receptor-like serine/threonine-protein kinase FLS2 (FLS2), Recombinant Protein

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Cat: RP01240
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana LRR receptor-like serine/threonine-protein kinase FLS2 (FLS2) , partial
Product Gene Name
FLS2 recombinant protein
Product Synonym Gene Name
FLS2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
LTCCKKKEKK IENSSESSLP DLDSALKLKR FEPKELEQAT DSFNSANIIG SSSLSTVYKG QLEDGTVIAV KVLNLKEFSA ESDKWFYTEA KTLSQLKHRN LVKILGFAWE SGKTKALVLP FMENGNLEDT IHGSAAPIGS LLEKIDLCVH IASGIDYLHS GYGFPIVHCD LKPANILLDS DRVAHVSDFG TARILGFRED GSTTASTSAF EGTIGYLAPE FAYMRKVTTK ADVFSFGIIM MELMTKQRPT SLNDEDSQDM TLRQLVEKSI GNGRKGMVRV LDMELGDSIV SLKQEEAIED FLKLCLFCTS SRPEDRPDMN EILTHLMKLR GKANSFREDR NEDREV
Sequence Positions
828-1173aa; Cytoplasmic domain
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
128,824 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
LRR receptor-like serine/threonine-protein kinase

NCBI/Uniprot Data

NCBI Accession #
NP_001330009.1
NCBI GI #
1063736481
NCBI GenBank Nucleotide #
NM_001344672.1
NCBI GeneID
834676
NCBI Official Full Name
Leucine-rich receptor-like protein kinase family protein
NCBI Official Symbol
FLS2
NCBI Official Synonym Symbols
FLAGELLIN-SENSITIVE 2; MPL12.13; MPL12.8; MPL12_13
NCBI Protein Information
Leucine-rich receptor-like protein kinase family protein
NCBI Summary
Encodes a leucine-rich repeat serine/threonine protein kinase that is expressed ubiquitously. FLS2 is involved in MAP kinase signalling relay involved in innate immunity. Essential in the perception of flagellin, a potent elicitor of the defense response. FLS2 is directed for degradation by the bacterial ubiquitin ligase AvrPtoB.
UniProt Gene Name
FLS2
UniProt Protein Name
LRR receptor-like serine/threonine-protein kinase FLS2
UniProt Synonym Protein Names
Protein FLAGELLIN-SENSING 2; Protein FLAGELLIN-SENSITIVE 2
UniProt Primary Accession #
Q9FL28
UniProt Secondary Accession #
Q0WVN3; Q84WF4
UniProt Related Accession #
Q9FL28
UniProt Comments
Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Flagellin-binding to the receptor is the first step to initiate the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6), resulting in enhanced resistance against pathogens. Binding to the effector AvrPto1 or to the phosphatase hopD2 from Pseudomonas syringae blocks the downstream plant immune response.

For research use only, not for clinical use.