LCA consists of four subunits of a 1-chain (molecular weight :5.7 kDa) and a 1-chain (molecular weight :17.5 kDa). This lectin is used to separate glycoconjugates in affinity columns. Two isomers, LCA-A and LCA-B, agglutinate human red blood cells, although they are not blood group specific. The activity of LCA is determined by agglutination with human blood and 2% human red blood cell suspension at a lectin concentration of 8µg/ml. LCA requires calcium and manganese ions to bind. See other LCA conjugations.
For research use only, not for clinical use.