NCBI Accession #
NP_001154351.1
NCBI GenBank Nucleotide #
NM_001160879.1
NCBI Official Full Name
isochorismate synthase 2
NCBI Official Symbol
ICS2
NCBI Official Synonym Symbols
ARABIDOPSIS ISOCHORISMATE SYNTHASE 2; ATICS2; F6A14.3; F6A14_3; isochorismate synthase 2
NCBI Protein Information
isochorismate synthase 2
NCBI Summary
Encodes a protein with isochorismate synthase activity involved in phylloquinone biosynthesis. Mutant studies of this gene's function suggest that its function is redundant with that of ICS1 (AT1G7410).
UniProt Synonym Gene Names
AtIcs2
UniProt Protein Name
Isochorismate synthase 2, chloroplastic
UniProt Synonym Protein Names
Isochorismate mutase 2; menF-like protein 2
UniProt Primary Accession #
Q9M9V6
UniProt Secondary Accession #
B2LWF5
UniProt Related Accession #
Q9M9V6
UniProt Comments
Involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death. Also involved in phylloquinone (vitamin K1) synthesis. Has no isochorismate pyruvate lyase (IPL) activity.