NCBI Accession #
NP_565090.1
NCBI GenBank Nucleotide #
NM_106129.4
NCBI Official Full Name
ADC synthase superfamily protein
NCBI Official Symbol
EDS16
NCBI Official Synonym Symbols
ARABIDOPSIS ISOCHORISMATE SYNTHASE 1; ATICS1; ENHANCED DISEASE SUSCEPTIBILITY TO ERYSIPHE ORONTII 16; F25A4.31; ICS1; ISOCHORISMATE SYNTHASE; ISOCHORISMATE SYNTHASE 1; SALICYLIC ACID INDUCTION DEFICIENT 2; SID2
NCBI Protein Information
ADC synthase superfamily protein
NCBI Summary
Encodes a protein with isochorismate synthase activity. Mutants fail to accumulate salicylic acid. Its function may be redundant with that of ICS2 (AT1G18870).
UniProt Synonym Gene Names
AtIcs1; IcsI; Eds16; Sid2
UniProt Protein Name
Isochorismate synthase 1, chloroplastic
UniProt Synonym Protein Names
Enhanced disease susceptibility 16; Eds16; Isochorismate mutase 1; Salicylic acid induction deficient 2; Sid2; menF-like protein 1
UniProt Primary Accession #
Q9S7H8
UniProt Secondary Accession #
O81522; Q3ECD2; Q9ASQ4
UniProt Related Accession #
Q9S7H8
UniProt Comments
Involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death. Also involved in phylloquinone (vitamin K1) synthesis. Has no isochorismate pyruvate lyase (IPL) activity.