NCBI Accession #
XP_002285637.1
NCBI GenBank Nucleotide #
XM_002285601.4
NCBI Official Full Name
inosine triphosphate pyrophosphatase
NCBI Official Symbol
LOC100245879
NCBI Official Synonym Symbols
ITPase; NTPase
NCBI Protein Information
inosine triphosphate pyrophosphatase
UniProt Gene Name
VIT_05s0051g00580
UniProt Synonym Gene Names
ITPase; Inosine triphosphatase; NTPase
UniProt Protein Name
Inosine triphosphate pyrophosphatase
UniProt Synonym Protein Names
Non-canonical purine NTP pyrophosphatase
UniProt Primary Accession #
F6HS55
UniProt Related Accession #
F6HS55
UniProt Comments
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.