Histone H3.3 (HIS3), Recombinant Protein
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Histone H3.3 (HIS3), Recombinant Protein

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Cat: RP19357
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Datasheet:

Product Info

Full Product Name
Recombinant Gossypium hirsutum Histone H3.3 (HIS3)
Product Gene Name
HIS3 recombinant protein
Product Synonym Gene Name
HIS3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
ARTKQTARKS TGGKAPRKQL ATKAARKSAP TTGGVKKPHR YRPGTVALRE IRKYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSHAVL ALQEAAEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA
Sequence Positions
2-136, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
15,406 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
XP_016687149.1
NCBI GI #
1029046926
NCBI GenBank Nucleotide #
XM_016831660.1
NCBI GeneID
107905089
NCBI Official Full Name
histone H3.3
NCBI Official Symbol
LOC107905089  
NCBI Protein Information
histone H3.3
UniProt Gene Name
HIS3  
UniProt Protein Name
Histone H3.3
UniProt Primary Accession #
Q71V89
UniProt Comments
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

For research use only, not for clinical use.