NCBI Accession #
NP_173418.1
NCBI GenBank Nucleotide #
NM_101844.2
NCBI Official Full Name
male-gamete-specific histone H3
NCBI Official Symbol
MGH3
NCBI Official Synonym Symbols
ATMGH3; F6F9.5; F6F9_5; male-gamete-specific histone H3; MALE-GAMETE-SPECIFIC HISTONE H3
NCBI Protein Information
male-gamete-specific histone H3
NCBI Summary
histone 3.3, male-gamete-specific expression. Direct target promoter of the male germline-specific transcription factor DUO1.
UniProt Protein Name
Histone H3-like 2
UniProt Synonym Protein Names
Male gamete-specific histone H3
UniProt Primary Accession #
Q9FXI7
UniProt Secondary Accession #
A6QRD3
UniProt Related Accession #
Q9FXI7
UniProt Comments
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling .