Histone H2A variant 1 (H2AV), Recombinant Protein
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Histone H2A variant 1 (H2AV), Recombinant Protein

Cat: RP01571
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Histone H2A variant 1 (H2AV)
Product Gene Name
H2AV recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAGKGGKGLV AAKTMAANKD KDKDKKKPIS RSARAGIQFP VGRIHRQLKT RVSAHGRVGA TAAVYTASIL EYLTAEVLEL AGNASKDLKV KRITPRHLQL AIRGDEELDT LIKGTIAGGG VIPHIHKSLI NKTTKE
Sequence Positions
1-136, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
14,541 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Histone

NCBI/Uniprot Data

NCBI Accession #
NP_001325682.1
NCBI GI #
1063716765
NCBI GenBank Nucleotide #
NM_001339683.1
NCBI GeneID
824621
NCBI Official Full Name
histone H2A 11
NCBI Official Symbol
HTA11
NCBI Official Synonym Symbols
histone H2A 11
NCBI Protein Information
histone H2A 11
NCBI Summary
Encodes HTA11, a histone H2A protein. Loss of all H2A.Z (triple mutant with HTA8 and HTA9) results in a reduction in DNA methylation of transposons but not that of genes. Loss of H2A.Z causes misregulation of many genes involved in the response to developmental and environmental cues, and that these genes tend to have high levels of gene-body H2A.Z.
UniProt Gene Name
H2AV
UniProt Protein Name
Histone H2A variant 1
UniProt Synonym Protein Names
H2A.F/Z 1; H2AvAt; HTA11
UniProt Primary Accession #
O23628
UniProt Related Accession #
O23628
UniProt Comments
Variant histone H2A which may replace conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling .

For research use only, not for clinical use.