NCBI Accession #
NP_187904.1
NCBI GenBank Nucleotide #
NM_112135.4
NCBI Official Full Name
histone acetyltransferase of the CBP family 5
NCBI Official Symbol
HAC5
NCBI Official Synonym Symbols
ATHPCAT4; histone acetyltransferase of the CBP family 5; HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 5; MGH6.20
NCBI Protein Information
histone acetyltransferase of the CBP family 5
NCBI Summary
Encodes an enzyme with histone acetyltransferase activity that can use both H3 and H4 histones as substrates. No single prior lysine acetylation is sufficient to block HAC5 acetylation of the H3 or H4 peptides, suggesting that HAC5 can acetylate any of several lysines present in the peptides. Di-acetylation of both lysines 9 and 14 on the H3 peptide significantly reduces the level of incorporated radioactive acetylation catalyzed by HAC5, indicating that HAC5 may acetylate either lysine 9 or lysine 14.
UniProt Synonym Gene Names
PCAT4
UniProt Protein Name
Histone acetyltransferase HAC5
UniProt Primary Accession #
Q9LE42
UniProt Secondary Accession #
Q8LRK5; Q8LRK6
UniProt Related Accession #
Q9LE42
UniProt Comments
Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.