NCBI Accession #
NP_178127.2
NCBI GenBank Nucleotide #
NM_106659.3
NCBI Official Full Name
histidine phosphotransfer protein 6
NCBI Official Synonym Symbols
AHP6; F18B13.18; F18B13_18; histidine phosphotransfer protein 6
NCBI Protein Information
histidine phosphotransfer protein 6
NCBI Summary
AHP6 lacks the conserved histidine residue (Asn83 in AHP6b), which is required for phosphotransfer, present in the other AHPs. AHP6 does not appear to have phosphotransfer activity. Acts as an inhibitor of cytokinin signaling by interacting with the phosphorelay machinery. Expressed in developing protoxylem and associated pericycle cell files. Negative regulator of cytokinin signaling. Expression is down-regulated by cytokinins. There are two alternatively spliced genes for this locus, AHP6a and AHP6b, differing in the length of the first exon. In ahp6-2 seedlings, only the AHP6a transcript is present. Members of the AHP gene family include: AT3G21510 (AHP1), AT3G29350 (AHP2), AT5G39340 (AHP3), AT3G16360 (AHP4), AT1G03430 (AHP5) and AT1G80100 (AHP6).
UniProt Synonym Gene Names
AHP6b
UniProt Protein Name
Pseudo histidine-containing phosphotransfer protein 6
UniProt Synonym Protein Names
Histidine-containing phosphotransfer protein 6
UniProt Primary Accession #
Q9SSC9
UniProt Secondary Accession #
Q104N2
UniProt Related Accession #
Q9SSC9
UniProt Comments
Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.