H3K37me1 | Histone H3 (Monomethylated Lys37)

Inquiry

Cat: PA01307

Size: 50 µg

Host: Rabbit

Clonality: Polyclonal

Confirmed reactivity: Human

Datasheet:

Product Info

Immunogen

KLH-conjugated synthetic peptide

Host

Rabbit

Clonality

Polyclonal

Purity

Immunogen affinity purified serum.

Format

Liquid

Storage

Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Application

Dot blot (Dot), Western blot (WB)

Recommended dilution

1 : 1000 (Dot), 1 µg/ml (WB)

Expected | apparent MW

15 kDa

Reactivity

Confirmed reactivity

Human

Predicted reactivity

Caenorhabditis elegans, Chicken, Drosophila melanogaster, Mouse, Plant, Rat, Xenopus sp.

Not reactive in

No confirmed exceptions from predicted reactivity are currently known

Additional information

This antibody preparation is provided in 20 mM Potassium Phosphate pH 7,2, 150 mM NaCl, 0,01% sodium azide and 30% glycerol

Description

Chromatin is the arrangement of DNA and proteins in which chromosomes are formed. Chromatin, in turn, is formed from nucleosomes, which consist of a set of four histones (H2A, H2B, H3, H4) wrapped around DNA. Chromatin is a very dynamic structure in which many post-translational modifications work together to activate or inhibit the replication, transcription, or repair availability of DNA. These markers determine which DNA is open and usually active (euchromatin) and which is tightly wound to prevent entry and activation (heterochromatin). Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, threonylation of lysine, biotinylation, and ubiquitination.

For research use only, not for clinical use.