Griffonia simplicifolia Lectin (GSL I) - Pure
Description
Griffonia simplicifolia lectin (GSLI) is affinitively purified from a woody climbing shrub native to Africa. GSLI consists of two subunits, A and B, which combine to form a tetramer structure, producing five isolates. The lectin binds terminal D-galactosyl residues and terminal n-acetyl - - Residual D-galactosaminyl. A-rich lectins preferentially agglutinate group A red blood cells and therefore appear to be specific to -n-acetylgalactosamine residues, while B-rich lectins preferentially agglutinate group B cells and are specific to -galactosamine residues. The specificity of the lectin for blood group B is higher than that for blood group A1. GSLI has been reported to bind to a variety of glycoproteins, including laminin. Due to some D-galactose residues are expressed in mouse tissue endothelial cells, and GSLI can exhibit highly specific glycosylation surface patterns in these cells.
Product Info
For research use only, not for clinical use.