Glycine-rich RNA-binding protein 8 (GRP8), Recombinant Protein
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Glycine-rich RNA-binding protein 8 (GRP8), Recombinant Protein

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Cat: RP00996
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Glycine-rich RNA-binding protein 8 (GRP8)
Product Gene Name
GRP8 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MSEVEYRCFV GGLAWATNDE DLQRTFSQFG DVIDSKIIND RESGRSRGFG FVTFKDEKAM RDAIEEMNGK ELDGRVITVN EAQSRGSGGG GGGRGGSGGG YRSGGGGGYS GGGGGGYSGG GGGGYERRSG GYGSGGGGGG RGYGGGGRRE GGGYGGGDGG SYGGGGGGW
Sequence Positions
1-169, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
5,884 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_195637.1
NCBI GI #
15235002
NCBI GenBank Nucleotide #
NM_120087.4
NCBI GeneID
830082
NCBI Official Full Name
cold, circadian rhythm, and RNA binding 1
NCBI Official Symbol
CCR1
NCBI Official Synonym Symbols
and RNA binding 1; ATGRP8; circadian rhythm; cold; GLYCINE-RICH PROTEIN 8; glycine-rich RNA-binding protein 8; GR-RBP8; GRP8; T22F8.160; T22F8_160
NCBI Protein Information
cold, circadian rhythm, and RNA binding 1
NCBI Summary
Encodes a glycine-rich protein with RNA binding domain at the N-terminus. Protein is structurally similar to proteins induced by stress in other plants. Gene expression is induced by cold. Transcript undergoes circadian oscillations that is depressed by overexpression of AtGRP7. A substrate of the type III effector HopU1 (mono-ADP-ribosyltransferase).
UniProt Gene Name
RBG8
UniProt Synonym Gene Names
CCR1; GR-RBP8; GRP8; AtGR-RBP8; AtGRP8; Protein CCR1
UniProt Protein Name
Glycine-rich RNA-binding protein 8
UniProt Synonym Protein Names
AtRBG8; Glycine-rich protein 8; AtGRP8; Protein COLD, CIRCADIAN RHYTHM, AND RNA BINDING 1; Protein CCR1
UniProt Primary Accession #
Q03251
UniProt Secondary Accession #
Q94CB0
UniProt Related Accession #
Q03251
UniProt Comments
Plays a role in RNA transcription or processing during stress. Binds RNAs and DNAs sequence with a preference to single-stranded nucleic acids. Involved in mRNA alternative splicing of numerous targets by modulating splice site selection. Negatively regulates the circadian oscillations of its own transcript as well as RBG7 transcript. Forms an interlocked post-transcriptional negative feedback loop with the RBG7 autoregulatory circuit. Both proteins negatively autoregulate and reciprocally crossregulate by binding to their pre-mRNAs and promoting unproductive splicing coupled to degradation via the NMD pathway. Target of the Pseudomonas syringae type III effector HopU1.

For research use only, not for clinical use.