Glutamate--cysteine ligase, chloroplastic (GSH1), Recombinant Protein
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Glutamate--cysteine ligase, chloroplastic (GSH1), Recombinant Protein

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Cat: RP00858
Size: 0.5 mg (E-Coli)/ 0.05 mg (Baculovirus)/ 0.5 mg (Yeast)/ 0.05 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Glutamate--cysteine ligase, chloroplastic (GSH1), partial
Product Gene Name
GSH1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
58,562 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_001190808.1
NCBI GI #
334186834
NCBI GenBank Nucleotide #
NM_001203879.2
NCBI GeneID
828409
NCBI Official Full Name
glutamate-cysteine ligase
NCBI Official Symbol
GSH1
NCBI Official Synonym Symbols
ATECS1; AtGSH1; CAD2; CADMIUM SENSITIVE 2; F7H19.290; F7H19_290; GAMMA-GLUTAMYL-CYSTEINE SYNTHETASE; GAMMA-GLUTAMYLCYSTEINE SYNTHETASE; glutamate-cysteine ligase; GLUTAMATE-CYSTEINE LIGASE; GSHA; PAD2; PHYTOALEXIN DEFICIENT 2; RML1; ROOT MERISTEMLESS 1
NCBI Protein Information
glutamate-cysteine ligase
NCBI Summary
Encodes the enzyme glutamate-cysteine ligase catalyzing the first, and rate-limiting, step of glutathione biosynthesis. Required for cell proliferation at the root tip. Involved in susceptibility to the bacterial pathogen Pseudomonas syringae. Mutants are phytoalexin defective.
UniProt Gene Name
GSH1
UniProt Synonym Gene Names
CAD2; GCL; PAD2; RML1; GCS; AtGCL
UniProt Protein Name
Glutamate--cysteine ligase, chloroplastic
UniProt Synonym Protein Names
Gamma-ECS; GCS; Gamma-glutamylcysteine synthetase; Protein ROOT MERISTEMLESS 1; AtGCL; Protein cadmium-sensitive 2; Protein phytoalexin-deficient 2
UniProt Primary Accession #
P46309
UniProt Secondary Accession #
O82759; P92951; Q93ZQ6; Q944I8; A0FGQ9
UniProt Related Accession #
P46309
UniProt Comments
Seems to play an important role in controlling the expression of resistance responses like the regulation of salicylic acid (SA) and phytoalexin (camalexin) production. Involved in resistance to fungal and bacterial pathogens. Required for the regulation of cell proliferation in root apical meristems through the GSH-dependent developmental pathway. Also participates in the detoxification process, the antioxidant response and is essential for embryo development and proper seed maturation.

For research use only, not for clinical use.