NCBI Accession #
NP_197423.1
NCBI GenBank Nucleotide #
NM_121927.3
NCBI Official Full Name
ADP glucose pyrophosphorylase large subunit 1
NCBI Official Symbol
APL1
NCBI Official Synonym Symbols
ADG2; ADP GLUCOSE PYROPHOSPHORYLASE 2; ADP glucose pyrophosphorylase large subunit 1; ADPG PYROPHOSPHORYLASE; T24G5.120; T24G5_120
NCBI Protein Information
ADP glucose pyrophosphorylase large subunit 1
NCBI Summary
Encodes the large subunit of ADP-glucose pyrophosphorylase which catalyzes the first, rate limiting step in starch biosynthesis. The large subunit plays a regulatory role whereas the small subunit (ApS) is the catalytic isoform. Four isoforms (ApL1-4) have been identified. ApL1 is the major large subunit isoform present in leaves. Mutational analysis of APS1 suggests that APL1 and APL2 can compensate for loss of APS1 catalytic activity,suggesting both have catalytic as well as regulatory functions.
UniProt Synonym Gene Names
APL1
UniProt Protein Name
Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic
UniProt Synonym Protein Names
ADP-glucose pyrophosphorylase; ADP-glucose synthase; AGPase S; Alpha-D-glucose-1-phosphate adenyl transferase
UniProt Primary Accession #
P55229
UniProt Secondary Accession #
O04929; Q9SXS1
UniProt Related Accession #
P55229
UniProt Comments
This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.