NCBI Accession #
NP_200323.1
NCBI GenBank Nucleotide #
NM_124894.5
NCBI Official Full Name
GDP-L-galactose phosphorylase VITAMIN C DEFECTIVE 5 (VTC5)
NCBI Official Symbol
VTC5
NCBI Official Synonym Symbols
MCO15.7; MCO15_7; VITAMIN C DEFECTIVE 5
NCBI Protein Information
GDP-L-galactose phosphorylase VITAMIN C DEFECTIVE 5 (VTC5)
NCBI Summary
Encodes a GDP-L-galactose phosphorylase, with similar biochemical properties as VTC2.
UniProt Synonym Gene Names
VTC2L
UniProt Protein Name
GDP-L-galactose phosphorylase 2
UniProt Synonym Protein Names
Protein VITAMIN C DEFECTIVE 5
UniProt Primary Accession #
Q9FLP9
UniProt Related Accession #
Q9FLP9
UniProt Comments
Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Acts as a phosphorylase rather than as a transferase. Uses preferentially GDP-L-galactose and GDP-D-glucose as substrates. Lower activity with GDP-L-fucose, very low activity with GDP-D-mannose, and no activity with UDP-D-glucose, UDP-D-galactose or ADP-D-glucose. Highly specific for inorganic phosphate as the guanylyl acceptor.