Gamma-glutamyl hydrolase (GGH), Recombinant Protein
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Gamma-glutamyl hydrolase (GGH), Recombinant Protein

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Cat: RP00045
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Gamma-glutamyl hydrolase (GGH)
Product Gene Name
GGH recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
KAATILLPSQ TGFDISRSPV CSAPDPNLNY RPVIGILSHP GDGASGRLSN ATDASSIAAS YVKLAESGGA RVIPLIFNEP EEILFQKLEL VNGVILTGGW AKEGLYFEIV KKIFNKVLER NDAGEHFPIY AICLGFELLT MIISQNRDIF EKMDARNSAS SLQFVENVNI QGTIFQRFPP ELLKKLGTDC LVMQNHRFGI SPQSFEGNIA LSNFFKIVTT CVDDNGKVYV STVQSTKYPV TGFQWHPEKN AFEWGSSKIP HSEDAIQVTQ HAANHLVSEA RKSLNRPESK KVLSNLIYNY KPTYCGYAGI GYDEVYIFTQ QRSLL
Sequence Positions
23-347, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
38,642 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Gamma-glutamyl hydrolase

NCBI/Uniprot Data

NCBI Accession #
NP_565186.2
NCBI GI #
30699349
NCBI GenBank Nucleotide #
NM_106515.4
NCBI GeneID
844204
NCBI Official Full Name
gamma-glutamyl hydrolase 2
NCBI Official Symbol
GGH2
NCBI Official Synonym Symbols
ATGGH2; gamma-glutamyl hydrolase 2
NCBI Protein Information
gamma-glutamyl hydrolase 2
NCBI Summary
The Arabidopsis protein AtGGH2 is a gamma-glutamyl hydrolase acting specifically on monoglutamates. The enzyme is involved in the tetrahydrofolate metabolism and located to the vacuole.
UniProt Gene Name
GGH2
UniProt Synonym Gene Names
GGH; GGH1; AtGGH2
UniProt Protein Name
Gamma-glutamyl hydrolase 2
UniProt Synonym Protein Names
Conjugase; GH; Gamma-Glu-X carboxypeptidase
UniProt Primary Accession #
O65355
UniProt Secondary Accession #
Q8VYT0; Q9ZV86
UniProt Related Accession #
O65355
UniProt Comments
Cleaves the polyglutamate sidechains of folate polyglutamates in the vacuole. Is important for polyglutamyl tail length determination before vacuolar exit. Plays a role on folate stability and intracellular folate content. Has endopeptidase activity against 4-amino-10-methylpteroyl penta-, tetra-, tri- and di-gamma-L-glutamate substrates and is responsible for the production of folic acid, also called pteroylglutamic acid (PteGlu) from teroylpolyglutamates.

For research use only, not for clinical use.