NCBI Accession #
NP_001321802.1
NCBI GenBank Nucleotide #
NM_001333320.1
NCBI Official Full Name
G-protein-coupled receptor 1
NCBI Official Symbol
GCR1
NCBI Official Synonym Symbols
F11A17.17; F11A17_17; G-protein-coupled receptor 1
NCBI Protein Information
G-protein-coupled receptor 1
NCBI Summary
encodes a protein similar to G-coupled receptor with 7 transmembrane regions. Overexpression studies suggest this gene is involved in dormancy and flowering. Reduction of expression results in decreased sensitivity to cytokinin.
UniProt Protein Name
G-protein coupled receptor 1
UniProt Primary Accession #
O04714
UniProt Secondary Accession #
O04214; Q8LPG0
UniProt Related Accession #
O04714
UniProt Comments
Together with GPA1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate(IP3) as a second messenger. Acts as a negative regulator of GPA1-mediated abscisic acid (ABA) responses in guard cells, and together with GPA1 and GB1 during seed germination and early seedling development. Promotes PI-PLC activity and IP3 accumulation. Involved in the blue light (BL) signaling. Together with GPA1 and ADT3, required for BL-mediated synthesis of phenylpyruvate and subsequently of phenylalanine (Phe), in etiolated seedlings. Probably involved in cytokinin signal transduction. Plays a positive role in gibberellin- (GA) and brassinosteroid- (BR) regulated seed germination, probably independently of a heterotrimeric G-protein. Mediates seed dormancy abolition, and promotes seed germination and flowering.