NCBI Accession #
NP_180598.1
NCBI GenBank Nucleotide #
NM_128592.3
NCBI Official Full Name
ferrochelatase 2
NCBI Official Synonym Symbols
ATFC-II; FC-II; ferrochelatase 2; T9D9.1
NCBI Protein Information
ferrochelatase 2
NCBI Summary
Encodes one of two ferrochelatase genes in Arabidopsis. Ferrochelatase is the terminal enzyme of heme biosynthesis. FC-II is speculated to operate in photosynthetic cytochromes
UniProt Synonym Gene Names
AtFC-II
UniProt Protein Name
Ferrochelatase-2, chloroplastic
UniProt Synonym Protein Names
Ferrochelatase-II
UniProt Primary Accession #
O04921
UniProt Secondary Accession #
O23623; Q7GB39
UniProt Related Accession #
O04921
UniProt Comments
Catalyzes the last step of heme biosynthesis by inserting ferrous iron into protoporphyrin IX to produce protoheme. Produces heme for photosynthetic cytochromes, and for proteins involved in abiotic and biotic stress responses (PubMed:24329537). May play a role in the quality control of individual chloroplasts during photo-oxidative stress through regulation of heme biosynthesis (PubMed:26494759).