NCBI Accession #
NP_171664.1
NCBI GenBank Nucleotide #
NM_100040.3
NCBI Official Full Name
ferric reduction oxidase 2
NCBI Official Symbol
FRO2
NCBI Official Synonym Symbols
ATFRO2; F22L4.12; F22L4_12; FERRIC CHELATE REDUCTASE DEFECTIVE 1; ferric reduction oxidase 2; FERRIC REDUCTION OXIDASE 2; FRD1
NCBI Protein Information
ferric reduction oxidase 2
NCBI Summary
Encodes the low-iron-inducible ferric chelate reductase responsible for reduction of iron at the root surface. It is likely to be the major Fe(III) chelate reductase in Arabidopsis iron metabolism. Coordinately regulated with IRT1, the major transporter responsible for high-affinity iron uptake from the soil, at both transcriptional and posttranscriptional levels. Steady state mRNA levels are regulated by several metals. Its transcription is regulated by FIT1.
UniProt Synonym Gene Names
FRD1; AtFRO2
UniProt Protein Name
Ferric reduction oxidase 2
UniProt Synonym Protein Names
Ferric-chelate reductase 2; Protein FERRIC CHELATE REDUCTASE DEFECTIVE 1
UniProt Primary Accession #
P92949
UniProt Secondary Accession #
Q9LMM3
UniProt Related Accession #
P92949
UniProt Comments
Flavocytochrome that transfers electrons across the plasma membrane to reduce ferric iron chelates to form soluble ferrous iron in the rhizosphere. May be involved in the delivery of iron to developing pollen grains. Acts also as a copper-chelate reductase. Involved in glycine betaine-mediated chilling tolerance and reactive oxygen species accumulation.