NCBI Accession #
NP_001105612.1
NCBI GenBank Nucleotide #
NM_001112142.1
NCBI Official Full Name
eukaryotic translation initiation factor 4E-1
NCBI Official Symbol
eif6
NCBI Official Synonym Symbols
eIF-4E; GRMZM2G002616
NCBI Protein Information
eukaryotic translation initiation factor 4E-1
UniProt Gene Name
eIF-4E-1
UniProt Synonym Gene Names
eIF4E-1
UniProt Protein Name
Eukaryotic translation initiation factor 4E-1
UniProt Synonym Protein Names
eIF-4F 25 kDa subunit; eIF-4F p26 subunit; mRNA cap-binding protein
UniProt Primary Accession #
O81481
UniProt Related Accession #
O81481
UniProt Comments
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.