NCBI Accession #
NP_176808.3
NCBI GenBank Nucleotide #
NM_105305.4
NCBI Official Full Name
Signal transduction histidine kinase, hybrid-type, ethylene sensor
NCBI Official Symbol
ETR1
NCBI Official Synonym Symbols
AtETR1; EIN1; ETHYLENE INSENSITIVE 1; ETHYLENE RESPONSE; ETHYLENE RESPONSE 1; ETR; HISTIDINE KINASE ETR1; T27F4.9; T27F4_9
NCBI Protein Information
Signal transduction histidine kinase, hybrid-type, ethylene sensor
NCBI Summary
Similar to prokaryote sensory transduction proteins. Contains a histidine kinase and a response regulator domain. Homodimer. Membrane component. Binds ethylene. Mutations affect ethylene binding and metabolism of other plant hormones such as auxin, cytokinins, ABA and gibberellic acid. Ethylene receptor. Has histidine kinase activity. Is regulated by RTE1. Mutations in ETR1 block ethylene stimulation of flavonol synthesis.
UniProt Synonym Gene Names
AtETR1
UniProt Protein Name
Ethylene receptor 1
UniProt Synonym Protein Names
Protein ETHYLENE RESPONSE 1
UniProt Primary Accession #
P49333
UniProt Related Accession #
P49333
UniProt Comments
Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling (PubMed:15466228, PubMed:15703053). In the presence of ethylene, the auto-kinase activity of ETR1 is inhibited and the non-phosphorylated kinase domain binds tightly to the corresponding domain of EIN2 (PubMed:20591837).