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Ethylene-overproduction protein 1 (ETO1), Recombinant Protein
Cat: RP00889
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Ethylene-overproduction protein 1 (ETO1) , partial
Product Gene Name
ETO1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
107,040 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Ethylene-overproduction protein
NCBI/Uniprot Data
NCBI Accession #
NP_190745.6
NCBI GI #
240255603
NCBI GenBank Nucleotide #
NM_115036.7
NCBI GeneID
824340
NCBI Official Full Name
tetratricopeptide repeat (TPR)-containing protein
NCBI Official Symbol
ETO1
NCBI Official Synonym Symbols
ARABIDOPSIS ETHYLENE OVERPRODUCER 1; ATEOL1; ETHYLENE OVERPRODUCER 1; ETHYLENE OVERPRODUCER1
NCBI Protein Information
tetratricopeptide repeat (TPR)-containing protein
NCBI Summary
Encodes a negative regulator of 1-aminocyclopropane-1-carboxylic acid synthase5(ACS5), which catalyze the rate-limiting step in ethylene biosynthesis. ETO1 directly interacts with ACS5 and inhibits its enzyme activity and targets it for degradation via proteasome-dependent pathway. It also interacts with CUL3 (a component of ubiquitin ligase complexes). eto1 (and eto3) mutations elevate ethylene biosynthesis by affecting the posttranscriptional regulation of ACS
UniProt Gene Name
ETO1
UniProt Synonym Gene Names
Protein ETO1
UniProt Protein Name
Ethylene-overproduction protein 1
UniProt Synonym Protein Names
Protein ETHYLENE OVERPRODUCER 1; Protein ETO1
UniProt Primary Accession #
O65020
UniProt Secondary Accession #
Q6PWY3; F4J4J0
UniProt Comments
Essential regulator of the ethylene pathway, which acts by regulating the stability of 1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes. May act as a substrate-specific adapter that connects ACS enzymes, such as ACS5, to ubiquitin ligase complexes, leading to proteasomal degradation of ACS enzymes.
For research use only, not for clinical use.