Erythrocyte lectins or lectins (ECL/ECA) are isolated lectins consisting of two subunits with molecular weights of 28000 and 26000. ECL binds to the membrane carbohydrate structure and serum glycoprotein of mammalian cells. May the shape of the lectin binding domain be related to Gal 1->4GlcNAc acts as a core binding site with an additional 1 to 4 sugar subsites that are most complementary to linear trisugars. Some oligosaccharides related to gal1 are the main structures of lectin binding. The binding activity of lectins can be lost by substitution of salicylic acid. This allows specific isolation and separation of mammalian glycoproteins.
For research use only, not for clinical use.