Erythrina cristagalli Lectin (ECL/ECA) - Pure
Description
Erythrocyte lectins or lectins (ECL/ECA) are affinity purified lectins consisting of two subunits with molecular weights of 28000 and 26000, respectively. ECL binds to the membrane carbohydrate structure and serum glycoprotein of mammalian cells. The shape of the lectin binding domain may be similar to that of a cavity, with Galβ1->4GlcNAc as the core binding site, with an additional 1 to 4 sugar subsites, most complementary to linear trisugars. Some oligosaccharides related to gal β1 are the main structures of lectin binding. The binding activity of lectins can be lost through sialic acid substitution. This allows specific isolation and separation of mammalian glycoproteins.
Product Info
For research use only, not for clinical use.