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E3 ubiquitin-protein ligase BRE1-like 2 (BRE1B), Recombinant Protein
Cat: RP12883
Species: Oryza sativa subsp. japonica (Rice)
Datasheet:
Product Info
Full Product Name
Recombinant Oryza sativa subsp. japonica E3 ubiquitin-protein ligase BRE1-like 2 (BRE1B), partial
Product Gene Name
BRE1B recombinant protein
Product Synonym Gene Name
BRE1B
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
96,498 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
XP_015614586.1
NCBI GI #
1002302404
NCBI GenBank Nucleotide #
XM_015759100.1
NCBI GeneID
4349420
NCBI Official Full Name
E3 ubiquitin-protein ligase BRE1-like 2
NCBI Official Symbol
LOC4349420
NCBI Official Synonym Symbols
BRE1B; OsJ_031219
NCBI Protein Information
E3 ubiquitin-protein ligase BRE1-like 2
UniProt Gene Name
BRE1B
UniProt Protein Name
E3 ubiquitin-protein ligase BRE1-like 2
UniProt Synonym Protein Names
RING-type E3 ubiquitin transferase BRE1-like 2Curated
UniProt Primary Accession #
Q336R3
UniProt Secondary Accession #
Q336R2; Q8S7C5; A3C7E7; B7EV99
UniProt Related Accession #
Q336R3
UniProt Comments
E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6.
For research use only, not for clinical use.