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E3 ubiquitin-protein ligase BRE1-like 1 (BRE1A), Recombinant Protein
Cat: RP12495
Species: Oryza sativa subsp. indica (Rice)
Datasheet:
Product Info
Full Product Name
Recombinant Oryza sativa subsp. indica E3 ubiquitin-protein ligase BRE1-like 1 (BRE1A), partial
Product Gene Name
BRE1A recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
100,399 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
NCBI/Uniprot Data
NCBI Accession #
A2XW69.2
NCBI GI #
152013368
NCBI Official Full Name
E3 ubiquitin-protein ligase BRE1-like 1
UniProt Gene Name
BRE1A
UniProt Protein Name
E3 ubiquitin-protein ligase BRE1-like 1
UniProt Synonym Protein Names
RING-type E3 ubiquitin transferase BRE1-like 1Curated
UniProt Primary Accession #
A2XW69
UniProt Secondary Accession #
B8ASX7
UniProt Comments
E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1. H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me. It thereby plays a central role in histone code and gene regulation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6.
For research use only, not for clinical use.