NCBI Accession #
NP_190399.2
NCBI GenBank Nucleotide #
NM_114685.4
NCBI Official Full Name
DP-E2F-like 1
NCBI Official Symbol
DEL1
NCBI Official Synonym Symbols
DP-E2F-like 1; DP-E2F-LIKE PROTEIN 1; E2F-LIKE 3; E2FE; E2L3
NCBI Protein Information
DP-E2F-like 1
NCBI Summary
E2F-like protein, an inhibitor of the endocycle, preserves the mitotic state of proliferating cells by suppressing transcription of genes that are required for cells to enter the DNA endoreduplication cycle.
UniProt Synonym Gene Names
DEL1; E2L3; ELP2
UniProt Protein Name
E2F transcription factor-like E2FE
UniProt Synonym Protein Names
DP-E2F-like protein 1; E2F-like repressor E2L3
UniProt Primary Accession #
Q8LSZ4
UniProt Secondary Accession #
Q8RYD8; Q9STS2
UniProt Related Accession #
Q8LSZ4
UniProt Comments
Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication.