DNA mismatch repair protein Msh3 (MSH3), Recombinant Protein
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DNA mismatch repair protein Msh3 (MSH3), Recombinant Protein

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Cat: RP01513
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana DNA mismatch repair protein Msh3 (MSH3) , partial
Product Gene Name
MSH3 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
119,366 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DNA mismatch repair protein

NCBI/Uniprot Data

NCBI Accession #
NP_194284.2
NCBI GI #
30686920
NCBI GenBank Nucleotide #
NM_118686.3
NCBI GeneID
828659
NCBI Official Full Name
homolog of DNA mismatch repair protein MSH3
NCBI Official Symbol
MSH3
NCBI Official Synonym Symbols
ATMSH3; homolog of DNA mismatch repair protein MSH3; M7J2.90; M7J2_90
NCBI Protein Information
homolog of DNA mismatch repair protein MSH3
NCBI Summary
encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH3 heterodimers bound 'insertion-deletion' DNA with three nucleotides (+AAG) or one nucleotide (+T) looped out much better than they bound DNA with a base/base mispair (T/G).
UniProt Gene Name
MSH3
UniProt Synonym Gene Names
AtMSH3
UniProt Protein Name
DNA mismatch repair protein MSH3
UniProt Synonym Protein Names
MutS protein homolog 3
UniProt Primary Accession #
O65607
UniProt Secondary Accession #
O81818
UniProt Related Accession #
O65607
UniProt Comments
Component of the post-replicative DNA mismatch repair system (MMR). Forms the heterodimer MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. MutS beta recognizes single base mismatches and trinucleotide insertion-deletion loops (IDL) in the DNA.

For research use only, not for clinical use.