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Disease resistance protein RPS5 (RPS5), Recombinant Protein
Cat: RP01864
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Disease resistance protein RPS5 (RPS5) , partial
Product Gene Name
RPS5 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
101,802 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Disease resistance protein
NCBI/Uniprot Data
NCBI Accession #
NP_001184970.1
NCBI GI #
334182494
NCBI GenBank Nucleotide #
NM_001198041.2
NCBI GeneID
837775
NCBI Official Full Name
Disease resistance protein (CC-NBS-LRR class) family
NCBI Official Symbol
RPS5
NCBI Official Synonym Symbols
DISEASE RESISTANCE PROTEIN RPS5; RESISTANT TO P. SYRINGAE 5; T28K15.5; T28K15_5
NCBI Protein Information
Disease resistance protein (CC-NBS-LRR class) family
NCBI Summary
Resistance gene, mediates resistance against the bacterial pathogen Pseudomonas syringae. Contains a putative nucleotide binding site composed of kinase-1a (or P-loop), kinase-2a, and putative kinase-3a domains, 13 imperfect leucine-rich repeats, a potential leucine zipper, and two uncharacterized motifs that are well conserved in products of previously isolated R genes. Confers resistance to Pseudomonas syringae strains that express avrPphB.
UniProt Gene Name
RPS5
UniProt Protein Name
Disease resistance protein RPS5
UniProt Synonym Protein Names
Resistance to Pseudomonas syringae protein 5; pNd3/pNd10
UniProt Primary Accession #
O64973
UniProt Secondary Accession #
O81402; O82098; O82100
UniProt Related Accession #
O64973
UniProt Comments
Disease resistance (R) protein that specifically recognizes the avrPphB type III effector avirulence protein from Pseudomonas syringae. Also confers resistance against Hyaloperonospora parasitica (downy mildew). Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Requires PBS1 to trigger the defense reaction against avrPphB. In case of infection by Pseudomonas syringae, AvrPphB triggers RPS5-mediated defense mechanism via the cleavage of PBS1, suggesting that the cleavage of PBS1 could trigger an exchange of ADP for ATP, thereby activating RPS5. May function as a fine-tuned sensor of alterations in the structure of the effector target PBS1.
For research use only, not for clinical use.