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DELLA protein RGA (RGA), Recombinant Protein
Cat: RP00044
Size: 0.5 mg (E-Coli)/ 0.05 mg (Baculovirus)/ 0.5 mg (Yeast)/ 0.05 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 0.5 mg (Baculovirus)/ 1 mg (Baculovirus)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana DELLA protein RGA (RGA) , partial
Product Gene Name
RGA recombinant protein
Product Synonym Gene Name
RGA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
LVHALMACAE AIQQNNLTLA EALVKQIGCL AVSQAGAMRK VATYFAEALA RRIYRLSPPQ NQIDHCLSDT LQMHFYETCP YLKFAHFTAN QAILEAFEGK KRVHVIDFSM NQGLQWPALM QALALREGGP PTFRLTGIGP PAPDNSDHLH EVGCKLAQLA EAIHVEFEYR GFVANSLADL DASMLELRPS DTEAVAVNSV FELHKLLGRP GGIEKVLGVV KQIKPVIFTV VEQESNHNGP VFLDRFTESL HYYSTLFDSL EGVPNSQDKV MSEVYLGKQI CNLVACEGPD RVERHETLSQ WGNRFGSSGL APAHLGSNAF KQASMLLSVF NSGQGYRVEE SNGCLMLGWH TRPLITTSAW K
Sequence Positions
221-581, Provide the GRAS domain
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
64,035 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
DELLA protein
NCBI/Uniprot Data
NCBI Accession #
NP_178266.1
NCBI GI #
15226311
NCBI GenBank Nucleotide #
NM_126218.3
NCBI GeneID
814686
NCBI Official Full Name
GRAS family transcription factor family protein
NCBI Official Symbol
RGA1
NCBI Official Synonym Symbols
F2I9.19; F2I9_19; REPRESSOR OF GA; REPRESSOR OF GA1-3 1; RGA
NCBI Protein Information
GRAS family transcription factor family protein
NCBI Summary
Member of the VHIID/DELLA regulatory family. Contains homopolymeric serine and threonine residues, a putative nuclear localization signal, leucine heptad repeats, and an LXXLL motif. Putative transcriptional regulator repressing the gibberellin response and integration of phytohormone signalling. DELLAs repress cell proliferation and expansion that drives plant growth. The protein undergoes degradation in response to GA via the 26S proteasome. RGA1 binds to PIF3 and inhibits its DNA binding activity and thus affects the expression of PIF3 regulated genes. RGA may be involved in reducing ROS accumulation in response to stress by up-regulating the transcription of superoxide dismutases. Represses GA-induced vegetative growth and floral initiation. Rapidly degraded in response to GA. Involved in fruit and flower development.
UniProt Gene Name
RGA
UniProt Synonym Gene Names
GRS; RGA1; AtGRAS-10
UniProt Protein Name
DELLA protein RGA
UniProt Synonym Protein Names
GAI-related sequence; GRAS family protein 10; AtGRAS-10; Repressor on the ga1-3 mutant; Restoration of growth on ammonia protein 1
UniProt Primary Accession #
Q9SLH3
UniProt Secondary Accession #
O23642; O23725; Q941D4
UniProt Related Accession #
Q9SLH3
UniProt Comments
Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenuation of auxin transport delaying its GA-induced degradation.
For research use only, not for clinical use.