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Dehydrodolichyl diphosphate synthase 1 (DPS) (CPT), Recombinant Protein
Cat: RP00314
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Dehydrodolichyl diphosphate synthase 1 (DPS)
Product Synonym Names
Recombinant Dehydrodolichyl diphosphate synthase 1 (DPS); Dehydrodolichyl diphosphate synthase 1; Dedol-PP synthase 1 EC= 2.5.1.87; Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) 1
Product Gene Name
CPT recombinant protein
Product Synonym Gene Name
DPS; ACPT
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MLSLLSSDSS LLSLLFLFLI PCLFITSYIG FPVFLLKLIG LIKIKAARDN EKRDEGTYVV REDGLQRELM PRHVAFILDG NRRWAKRAGL TTSQGHEAGA KRLIDIAELC FELGVHTVSA FAFSTENWGR DKIEIDNLMS LIQHYRNKSN IKFFHRSEVR VSVIGNKTKI PESLLKEIHE IEEATKGYKN KHLIMAVDYS GKFDIMHACK SLVKKSEKGL IREEDVDEAL IERELLTNCS DFPSPDLMIR TSGEQRISNF FLWQLAYSEL FFSPVFWPDF DKDKLLEALA SYQRRERRFG CRV
Sequence Positions
1-303
Chromosome Location
Chromosome: 2; NC_003071.7 (9966130..9967772, complement). Location: chromosome: 2
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
34,975 Da
Storage
Store at -20℃. For extended storage, store at -20 or -80℃.
Protein Family
Carboxypeptidase
NCBI/Uniprot Data
NCBI Accession #
NP_565551.1
NCBI GI #
18400264
NCBI GenBank Nucleotide #
NM_127905.3
NCBI GeneID
816873
NCBI Official Full Name
dehydrodolichyl diphosphate synthase 1
NCBI Official Symbol
CPT
NCBI Official Synonym Symbols
ACPT; cis-prenyltransferase; CPT
NCBI Protein Information
dehydrodolichyl diphosphate synthase 1
NCBI Summary
encodes cis-prenyltransferase
UniProt Gene Name
DPS
UniProt Synonym Gene Names
ACPT; Dedol-PP synthase 1
UniProt Protein Name
Dehydrodolichyl diphosphate synthase 1
UniProt Synonym Protein Names
Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) 1
UniProt Entry Name
DDPS1_ARATH
UniProt Primary Accession #
O80458
UniProt Secondary Accession #
Q9SEB8
UniProt Related Accession #
T52648
UniProt Comments
Function: Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.Catalytic activity: (2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate + ditrans,polycis-polyprenyl diphosphate (n = 10-55).Cofactor: Magnesium.Pathway: Protein modification; protein glycosylation.Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Tissue specificity: Expressed in low levels in the whole plant. Preferentially expressed in roots.Sequence similarities: Belongs to the UPP synthase family.Biophysicochemical propertiesKinetic parameters:KM=0.13 µM for farnesyl diphosphate (FPP)KM=3.62 µM for geranylgeranyl diphosphate (GGPP)KM=23 µM for isopentenyl diphosphate (IPP)
For research use only, not for clinical use.