Cyclin-dependent kinase inhibitor 2 (KRP2), Recombinant Protein
  1. Home
  2. Products
  3. Plant Proteins
  4. Recombinant Plant Proteins
  5. Recombinant Arabidopsis Thaliana Protein
Products
Online Inquiry

Cyclin-dependent kinase inhibitor 2 (KRP2), Recombinant Protein

Inquiry
Cat: RP01549
Size: 0.02 mg (E-Coli)/ 0.1 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 1 mg (E-Coli)/ 0.1 mg (Baculovirus)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Cyclin-dependent kinase inhibitor 2 (KRP2)
Product Gene Name
KRP2 recombinant protein
Product Synonym Gene Name
KRP2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MAAVRRRERD VVEENGVTTT TVKRRKMEEE VDLVESRIIL SPCVQATNRG GIVARNSAGA SETSVVIVRR RDSPPVEEQC QIEEEDSSVS CCSTSEEKSK RRIEFVDLEE NNGDDRETET SWIYDDLNKS EESMNMDSSS VAVEDVESRR RLRKSLHETV KEAELEDFFQ VAEKDLRNKL LECSMKYNFD FEKDEPLGGG RYEWVKLNP
Sequence Positions
1-209aa; Full Length
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
24,037 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Cyclin-dependent kinase inhibitor

NCBI/Uniprot Data

NCBI Accession #
NP_190632.1
NCBI GI #
15229815
NCBI GenBank Nucleotide #
NM_114923.4
NCBI GeneID
824226
NCBI Official Full Name
KIP-related protein 2
NCBI Official Symbol
KRP2
NCBI Official Synonym Symbols
ICK2; KIP-related protein 2; KIP-RELATED PROTEIN 2
NCBI Protein Information
KIP-related protein 2
NCBI Summary
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. Gene was isolated from a yeast two hybrid screen as an interacting protein of CDC2A. Recombinant protein has a strong kinase inhibitor activity in vitro. Transcript is expressed in all tissues examined but is differentially distributed from ICK1. Controls the onset of the endoreduplication cycle through inhibition of CDKA;1. The KRP2 protein abundance is regulated by proteolysis through CDKB1;1 phosphorylation.
UniProt Gene Name
KRP2
UniProt Synonym Gene Names
ICK2
UniProt Protein Name
Cyclin-dependent kinase inhibitor 2
UniProt Synonym Protein Names
Inhibitor/interactor of CDK protein 2; KIP-related protein 2
UniProt Primary Accession #
Q9SCR2
UniProt Related Accession #
Q9SCR2
UniProt Comments
Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity. Regulates cell division which is crucial for plant growth, development and morphogenesis. May regulate early lateral root initiation by blocking the G1/S phase transition. Controls the mitosis-to-endocycle transition and the onset of the endoreduplication cycle during leaf development through inhibition of mitotic CDKA-1 kinase complexes. Specifically targets CDKA-1.

For research use only, not for clinical use.