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Cullin-1 (CUL1), Recombinant Protein
Cat: RP01460
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Cullin-1 (CUL1) , partial
Product Gene Name
CUL1 recombinant protein
Product Synonym Gene Name
CUL1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
86,302 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Cullin
NCBI/Uniprot Data
NCBI Accession #
NP_001031575.1
NCBI GI #
79324981
NCBI GenBank Nucleotide #
NM_001036498.3
NCBI GeneID
825648
NCBI Official Full Name
cullin 1
NCBI Official Symbol
CUL1
NCBI Official Synonym Symbols
ATCUL1; AUXIN RESISTANT 6; AXR6; cullin 1; T10P11.26; T10P11_26
NCBI Protein Information
cullin 1
NCBI Summary
Encodes a cullin that is a component of SCF ubiquitin ligase complexes involved in mediating responses to auxin and jasmonic acid. Homozygous auxin-resistant mutants arrest growth soon after germination, lacking a root and hypocotyl. Heterozygotes display a variety of phenotypes consistent with impaired auxin response.
UniProt Gene Name
CUL1
UniProt Protein Name
Cullin-1
UniProt Primary Accession #
Q94AH6
UniProt Secondary Accession #
O22770; Q56W31
UniProt Related Accession #
Q94AH6
UniProt Comments
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Regulator of mitotic processes which plays a role during gametogenesis and embryogenesis. Together with SKP1, RBX1 and a F-box protein, it forms a SCF complex. The functional specificity of this complex depends of the type of F-box protein. SCF(UFO) is implicated in floral organ development. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1/ZTL), SCF(ADO2/LKP2), SCF(ADO3/FKF1) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling.
For research use only, not for clinical use.