COP9 signalosome complex subunit 1 (CSN1), Recombinant Protein
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COP9 signalosome complex subunit 1 (CSN1), Recombinant Protein

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Cat: RP01924
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Yeast)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana COP9 signalosome complex subunit 1 (CSN1)
Product Gene Name
CSN1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MERDEEASGP MMEMCTNGGE ETSNRRPIIS GEPLDIEAYA ALYKGRTKIM RLLFIANHCG GNHALQFDAL RMAYDEIKKG ENTQLFREVV NKIGNRLGEK YGMDLAWCEA VDRRAEQKKV KLENELSSYR TNLIKESIRM GYNDFGDFYY ACGMLGDAFK NYIRTRDYCT TTKHIIHMCM NAILVSIEMG QFTHVTSYVN KAEQNPETLE PMVNAKLRCA SGLAHLELKK YKLAARKFLD VNPELGNSYN EVIAPQDIAT YGGLCALASF DRSELKQKVI DNINFRNFLE LVPDVRELIN DFYSSRYASC LEYLASLKSN LLLDIHLHDH VDTLYDQIRK KALIQYTLPF VSVDLSRMAD AFKTSVSGLE KELEALITDN QIQARIDSHN KILYARHADQ RNATFQKVLQ MGNEFDRDVR AMLLRANLLK HEYHARSARK L
Sequence Positions
1-441, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
50,579 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.

NCBI/Uniprot Data

NCBI Accession #
NP_567109.1
NCBI GI #
18411857
NCBI GenBank Nucleotide #
NM_115978.4
NCBI GeneID
825286
NCBI Official Full Name
COP9 signalosome complex subunit 1
NCBI Official Symbol
FUS6
NCBI Official Synonym Symbols
ARABIDOPSIS THALIANA FUSCA 6; AtCSN1; ATFUS6; ATSK31; CONSTITUTIVE PHOTOMORPHOGENIC 11; COP11; COP9 SIGNALOSOME SUBUNIT 1; CSN1; EMB78; EMBRYO DEFECTIVE 78; FUSCA 6; SHAGGY-LIKE KINASE 31; SK31
NCBI Protein Information
COP9 signalosome complex subunit 1
NCBI Summary
Represses photomorphogenesis and induces skotomorphogenesis in the dark. Component of the nuclear-localized COP9 complex. Mutants display striking purple coloration due to anthocyanin accumulation in their cotyledons, first become defective during embryogenesis and exhibit limited seedling development.
UniProt Gene Name
CSN1
UniProt Synonym Gene Names
COP11; FUS6; CSN complex subunit 1
UniProt Protein Name
COP9 signalosome complex subunit 1
UniProt Synonym Protein Names
Constitutive photomorphogenesis protein 11; Protein FUSCA 6
UniProt Primary Accession #
P45432
UniProt Secondary Accession #
Q8GYL2; Q9C5F0; Q9M2E9; Q9M4G0
UniProt Related Accession #
P45432
UniProt Comments
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. In the complex, it plays a central role in CSN assembly.

For research use only, not for clinical use.