Casein kinase II subunit beta (CKB1), Recombinant Protein
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Casein kinase II subunit beta (CKB1), Recombinant Protein

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Cat: RP01632
Size: 0.02 mg (E-Coli)/ 0.02 mg (Yeast)/ 0.1 mg (E-Coli)/ 0.1 mg (Yeast)/ 0.02 mg (Baculovirus)/ 0.02 mg (Mammalian-Cell)/ 0.1 mg (Baculovirus)/ 1 mg (E-Coli)/ 1 mg (Yeast)/ 0.1 mg (Mammalian-Cell)/ 1 mg (Baculovirus)/ 0.5 mg (Mammalian-Cell)
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:

Product Info

Full Product Name
Recombinant Arabidopsis thaliana Casein kinase II subunit beta (CKB1)
Product Gene Name
CKB1 recombinant protein
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Sequence
MYRDRGTVNS RPEVVDRKRI NDALERPSPS TSRQVNGKGK GTVTAATTTA NLIGKQQSNN INHRDSRSAS LSKNNTVSDD ESDTDSEESD VSGSDGEDTS WISWFCNLRG NEFFCEVDDD YIQDDFNLCG LSSLVPYYEY ALDLILDVES SQGEMFTEEQ NELIESAAEM LYGLIHARYI LTSKGLAAML DKYKNYDFGR CPRVYCCGQP CLPVGQSDLP RSSTVKIYCP KCEDIYYPRS KYQGNIDGAY FGTTFPHLFL MTYGHLKPAK ATQNYVQRVF GFKLHKP
Sequence Positions
1-287, Full length protein
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
32,355 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Casein kinase

NCBI/Uniprot Data

NCBI Accession #
NP_199519.1
NCBI GI #
15238013
NCBI GenBank Nucleotide #
NM_124079.4
NCBI GeneID
834754
NCBI Official Full Name
casein kinase II beta chain 1
NCBI Official Symbol
CKB1
NCBI Official Synonym Symbols
casein kinase II beta chain 1; casein kinase II beta chain 1; CASEIN KINASE II BETA SUBUNIT CKB1; K14A3.3; K14A3_3
NCBI Protein Information
casein kinase II beta chain 1
NCBI Summary
Regulatory subunit beta of casein kinase II (CK2). purified CKB1 resulted in up 100-fold stimulation of casein kinase activity compared with the CKA1 activity alone. Forms a tetrameric complex with CKA1 (CKA1(2)CKB1(2)). One known substrate of CK2 is Phytochrome Interacting Factor 1 (PIF1). CK2-mediated phosphorylation enhances the light-induced degradation of PIF1 to promote photomorphogenesis.
UniProt Gene Name
CKB1
UniProt Synonym Gene Names
CK II beta-1Curated
UniProt Protein Name
Casein kinase II subunit beta-1
UniProt Primary Accession #
P40228
UniProt Related Accession #
P40228
UniProt Comments
Plays a complex role in regulating the basal catalytic activity of the alpha subunit. The tetrameric holoenzyme CK2, composed of two alpha and two beta subunits, phosphorylates the transcription factor GBFl, resulting in stimulation of its DNA binding activity (PubMed:7696877). CK2 phosphorylates the transcription factor PIF1 after an exposure to light, resulting in a proteasome-dependent degradation of PIF1 and promotion of photomorphogenesis (PubMed:21330376). CK2 phosphorylates translation initiation factors. May participate in the regulation of the initiation of translation (PubMed:19509278, PubMed:19509420). Stimulates the binding of CCA1 to promoters (Probable).

For research use only, not for clinical use.