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Carotenoid cleavage dioxygenase 8, chloroplastic (CCD8), Recombinant Protein
Cat: RP01500
Species: Arabidopsis thaliana (Mouse-ear cress)
Datasheet:
Product Info
Full Product Name
Recombinant Arabidopsis thaliana Carotenoid cleavage dioxygenase 8, chloroplastic (CCD8) , partial
Product Gene Name
CCD8 recombinant protein
Product Synonym Gene Name
CCD8
Purity
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Molecular Weight
63,957 Da
Storage
Store at -20℃. For long-term storage, store at -20℃ or -80℃. Store working aliquots at 4℃ for up to one week. Repeated freezing and thawing is not recommended.
Protein Family
Carotenoid cleavage dioxygenase
NCBI/Uniprot Data
NCBI Accession #
NP_195007.2
NCBI GI #
30689501
NCBI GenBank Nucleotide #
NM_119434.4
NCBI GeneID
829417
NCBI Official Full Name
carotenoid cleavage dioxygenase 8
NCBI Official Symbol
CCD8
NCBI Official Synonym Symbols
ATCCD8; carotenoid cleavage dioxygenase 8; MAX4; MORE AXILLARY BRANCHING 4; T16I18.20; T16I18_20
NCBI Protein Information
carotenoid cleavage dioxygenase 8
NCBI Summary
Encodes a protein with similarity to carotenoid cleaving deoxygenases, the enzymes that cleave beta-carotene. Involved in the production of a graft transmissable signal to suppress axillary branching. Protein is localized to chloroplast stroma and expressed primarily in root tip. Mutants in the gene exhibit increased shoot branching, and light-dependent defects in hook opening and hypocotyl/root elongation. Only upregulated by auxin in the root and hypocotyl, and this is not required for the inhibition of shoot branching.
UniProt Gene Name
CCD8
UniProt Synonym Gene Names
MAX4; NCED8; AtCCD8
UniProt Protein Name
Carotenoid cleavage dioxygenase 8, chloroplastic
UniProt Synonym Protein Names
AtNCED8; Protein MORE AXILLARY BRANCHING 4; Protein MORE AXILLARY GROWTH 4
UniProt Primary Accession #
Q8VY26
UniProt Secondary Accession #
Q9M079
UniProt Related Accession #
Q8VY26
UniProt Comments
Involved in strigolactones biosynthesis by cleaving the C(27) 9-cis-10'-apo-beta-carotenal produced by CCD7. Produces the C(19) carlactone and a C8 hydroxyaldehyde. Also shows lower activity with all-trans-10'-apo-beta-carotenal producing a C9 dialdehyde and the C(18) 13-apo-beta-carotenone. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds. Also active on other carotenoid substrates like licopene or zeaxanthin.
For research use only, not for clinical use.