NCBI Accession #
NP_181687.1
NCBI GenBank Nucleotide #
NM_129719.4
NCBI Official Full Name
autoinhibited Ca(2+)-ATPase, isoform 4
NCBI Official Symbol
ACA4
NCBI Official Synonym Symbols
''autoinhibited Ca(2+)-ATPase; autoinhibited Ca(2+)-ATPase; isoform 4; isoform 4''; T32G6.8; T32G6_8
NCBI Protein Information
autoinhibited Ca(2+)-ATPase
NCBI Summary
Encodes a calmodulin-regulated Ca(2+)-ATPase that improves salt tolerance in yeast. Localized to the vacuole. Lesion mimic phenotype when mutation in the gene is combined with a mutation in ACA11. Lesion mimic phenotype of double knockout can be suppressed by nutritional supplements that increase anion levels (e.g. 15 mM Nitrate, Chloride, or Phosphate).
UniProt Protein Name
Calcium-transporting ATPase 4, plasma membrane-type
UniProt Synonym Protein Names
Ca(2+)-ATPase isoform 4
UniProt Primary Accession #
O22218
UniProt Related Accession #
O22218
UniProt Comments
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into small vacuoles.